KMID : 0604020170320040359
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Korean Journal of Critical Care Medicine 2017 Volume.32 No. 4 p.359 ~ p.362
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Malignant Syndrome in Parkinson¡¯s Disease Similar to Severe Infection
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Lee Dong-Hun
Moon Jeong-Mi Cho Young-Soo
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Abstract
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A 70-year-old woman with Parkinson¡¯s disease was admitted to the emergency department with altered consciousness, fever and convulsive movements without experiencing withdrawal from antiparkinsonian medication. Six hours after the emergency department visit, the patient had a hyperpyrexia (> 40¡ÆC) and a systolic blood pressure of 40 mmHg. There was no evidence of bacterial infection based on extensive workups. The patient was discharged without aggravation of Parkinson¡¯s disease symptoms after treatment that included administration of dantrolene sodium, enforcement of continuous renal replacement therapy and cooling blankets. Malignant syndrome should be suspected if high fever occurs in Parkinson¡¯s disease patients without evidence of a definitive infection.
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KEYWORD
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malignant syndrome, fever, dehydration, parkinson disease.
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